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Our facility

The IMATHERa team, part of the nuclear medicine department headed by Professor Alexandre Cochet (PU-PH), has a 1000 m² laboratory entirely dedicated to preclinical imaging and is accredited by the French Nuclear Safety Authority (ASN) and the Departmental Directorate for the Protection of Populations (DDPP). Its highly specialised staff includes a multidisciplinary team led by Dr Bertrand Collin, radiopharmacist-teacher-researcher in charge of the team, Dr Alexandra Oudot, deputy team leader, Dr Pierre-Simon Bellaye, head of academic research, Dr Alexandre Dias, researcher, Dr Alan Courteau, researcher in PET/RMI and Alex Helbling, study director. The team also includes a radiophysicist (Dr Jean-Marc Vrigneaud), two people responsable for radiation protection (Lydie Houot and Mickael Pichon). PIRP’s work is supported by a highly specialised technical team (Romain Ruffin, Lucie Maitre, Damien Loichot, Lil Proukhnitzky, Mélanie Guillemin and John Simonet) and PhD students (Agnieszka Kownacka, Jame Frenay, Romain Fontaine-Tuffery, Camille Petitot, Sarah Jedidi and Adam Laouafa).

Thanks to the radiochemistry, radiolabelling and quality control laboratories, it is possible to design innovative customised imaging probes using the latest generation equipment. Molecular probes are then evaluated in vitro and in vivo using a full range of equipment to adapt the detection technology to the biological problem: scintigraphy camera coupled to a scanner, PET (positron emission tomography) coupled to a scanner, PET coupled to MRI (magnetic resonance imaging), optical imaging or 2D imaging.

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In each study carried out at IMATHERa, particular attention is paid to getting as close as possible to the clinical conditions encountered in patients by adapting the imaging probes developed as closely as possible to living conditions. To achieve this, models that are as close as possible to human pathology are used, using the same imaging modalities as in the clinical nuclear medicine department.

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