New Publication

[Publication scientifique] L’équipe IMATHERA (IMAgerie préclinique et THErapie par les radiations ionisantes, #BioSanD – UMS #INSERM  58, Dr @Bertand Collin, #ICMUB – UMR CNRS 6302) du #CGFL est ravi d’annoncer la publication de ses travaux de recherche préclinique dans la revue Theranostics en collaboration avec l’équipe #INSERM U1231 (Dr @Carmen Garrido, Pr @Philippe Bonniaud). Ces travaux menés par le Dr @Alexandre Dias et dirigés par le Dr @Pierre-Simon Bellaye démontrent l’intérêt de l’imagerie du collagène pour la détection et la prédiction de la progression de la fibrose pulmonaire et représente un outil d’imagerie non invasif capable de surveiller l’efficacité des thérapies anti-fibrose. Cette étude ouvre la voie à des investigations plus poussées qui pourraient contribuer à l’amélioration de la prise en charge des patients atteints de fibrose pulmonaire idiopathique. Plus d’informations ici : https://www.thno.org/v15p2092.htm

[Scientific publication] The #CGFL‘s IMATHERA team (IMAging and radiation THERapy, #BioSanD – UMS #INSERM 58, Dr @Bertand Collin, #ICMUB – UMR CNRS 6302) is delighted to announce the publication of its preclinical research work in the journal Theranostics in collaboration with the #INSERM U1231 team (Dr @Carmen Garrido, Pr @Philippe Bonniaud). This work performed by Dr @Alexandre Dias and led by Dr @Pierre-Simon Bellaye demonstrates the value of collagen imaging for detecting and predicting the progression of pulmonary fibrosis, and represents a non-invasive imaging tool capable of monitoring the efficacy of anti-fibrosis therapies. This study paves the way for further investigations that could contribute to improving the management of patients with idiopathic pulmonary fibrosis. Read more here: https://www.thno.org/v15p2092.htm

#Research, #CGFL, #IPF, #Fondation du souffle, #Theranostics

[Publication scientifique] L’équipe IMATHERA (IMAgerie préclinique et THErapie par les radiations ionisantes, #BioSanD – UMS #INSERM  58, Dr @Bertand Collin, #ICMUB – UMR CNRS 6302) du #CGFL est ravi d’annoncer la publication de ses travaux de recherche préclinique dans la revue Thorax en collaboration avec l’équipe #INSERM U1231 (Dr @Carmen Garrido, Pr @Philippe Bonniaud). Ces travaux dirigés par le Dr @Pierre-Simon Bellaye démontrent l’intérêt de l’imagerie des macrophages de type 2 pour la détection et la prédiction de la progression de la fibrose pulmonaire et représente un outil d’imagerie non invasif capable de surveiller l’efficacité des thérapies anti-fibrotiques. Cette étude ouvre la voie à des investigations plus poussées qui pourraient contribuer à l’amélioration de la prise en charge des patients atteints de fibrose pulmonaire idiopathique. Plus d’informations ici : https://thorax.bmj.com/content/thoraxjnl/early/2024/07/20/thorax-2023-221168.full.pdf

[Scientific publication] The #CGFL‘s IMATHERA team (IMAging and radiation THERapy, #BioSanD – UMS #INSERM 58, Dr @Bertand Collin, #ICMUB – UMR CNRS 6302) is delighted to announce the publication of its preclinical research work in the journal Thorax in collaboration with the #INSERM U1231 team (Dr @Carmen Garrido, Pr @Philippe Bonniaud). This work led by Dr @Pierre-Simon Bellaye demonstrates the value of type 2 macrophage imaging for detecting and predicting the progression of pulmonary fibrosis, and represents a non-invasive imaging tool capable of monitoring the efficacy of anti-fibrosis therapies. This study paves the way for further investigations that could contribute to improving the management of patients with idiopathic pulmonary fibrosis. Read more here: https://thorax.bmj.com/content/thoraxjnl/early/2024/07/20/thorax-2023-221168.full.pdf

#Research, #CGFL, #IPF, #Fondation du souffle, #Theranostics

IMATHERA (CGFL, Dr Bertand Collin, Associate Professor, ICMUB – UMR CNRS 6302) was present at the “5ème Journées Scientifiques du GDR Agents d’Imagerie Moléculaire (GDR AIM)” in Paris. Romain Fontaine-Tuffery (ICMUB – UMR CNRS 6302/CGFL) presented his research work as part of the EQUIPEX IMAPPI (ANR-10-EQPX-0005) on the synthesis of fluorinated metal porphyrin platforms for PET imaging and photodynamic therapy. This work is under the direction of Dr Bertrand Collin (CGFL/ICMUB) and Dr Richard Decreau (Associate Professor, ICMUB – UMR CNRS 6302).

IMATHERa (CGFL, Dr Bertand Collin, ICMUB – UMR CNRS 6302) was present at the “Journées de recherche respiratoires (J2R)” in Tours. Dr Alexandre Dias (CGFL) presented his research work as part of the HYMAGE-IPF project (ANR-20-CE17-0005) on the development of a theranostic strategy targeting Gp96 in pulmonary fibrosis. This work, under the direction of Dr Pierre-Simon Bellaye (CGFL), was carried out in collaboration with Pr Philippe Bonniaud’s (CHU de Dijon – INSERM U1231, HSP-pathies) team led by Dr Carmen Garrido (INSERM U1231, HSP-pathies).

IMATHERa (CGFL) was present at the European Congress of Nuclear Medicine (EANM) in Vienna. Drs Alan Courteau and Bertrand Collin (CGFL / ICMUB – UMR CNRS 6302) presented their research work part of the EQUIPEX IMAPPI (ANR-10-EQPX-0005) program on preclinical multi-animal PET/MRI imaging and preclinical theranostic PET imaging of CD30-positive cancers with [Zr89]Zr-DFO-Brentuximab vedotin, respectively.

A new review article, co-authored by Drs Jame Frenay and Pierre-Simon Bellaye (Supervisor: Dr Alexandre Dias), has just been published by IMATHERa (CGFL – Dr B. Collin, ICMUB UMR CNRS 6302). This literature review highlights the fact that IL-1RAP, a receptor involved in the inflammatory response, is now considered as a promising therapeutic target in several hematological and solid cancers: see publication.

A new review article, co-authored by Drs Alexandre Dias and Alan Courteau, has just been published by IMATHERa (CGFL – Dr B. Collin, ICMUB UMR CNRS 6302).

This literature review highlights the theranostic potential of innovative superparamagnetic nanoparticles for cancer immunotherapy via magnetic hyperthermia and targeting of M2 macrophages: https://www.mdpi.com/1999-4923/14/11/2388.